产品货号:
Z34152
中文名称:
C-MYC/MYC抗体
英文名称:
Anti-C-MYC/MYC Antibody (Clone#9E10)
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-C-MYC/MYC Antibody (Clone#9E10) |
指标别名 | bHLHe39;c Myc;c-Myc;MRTL;MYC;Myc proto oncogene protein;Proto oncogene c Myc;Transcription factor p64 |
克隆性 | Monoclonal |
检验物种 | human |
应用范围 | WB,IHC,ICC |
基因名称 | MYC |
克隆号 | 9E10 |
抗体来源 | Mouse |
抗体类型 | IgG1 |
免疫原 | Synthetic peptide corresponding to residues 408-439 of the human p62c-Myc protein. |
实际分子量 | 49KD |
成分 | 200μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | Ascites |
浓度 | 200μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | C-Myc is an oncogene that functions both in the stimulation of cell proliferation and in apoptosis.c-Myc elicits its oncogenic activity by causing immortalization,and to a lesser extent the transformation of cells,in addition to several other mechanisms.The c-MYC proto-oncogene encodes a transcription factor that is critical for cell growth and proliferation.It is one of the genes frequently altered in cancer cells in which it exhibits constitutive activity.Downregulation of c-Myc is critical for 2-Methoxyestradiol(2ME2)-induced oxidative stress and apoptosis in AML cells.And its up-regulation is important for promoting lymphocyte cell division,and demonstrating that GFP-c-Myc expression is a marker of proliferating lymphocytes in vivo. |
Uniprot ID | P01106 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (ZN1928) for Western blot,and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (ZN1866) for IHC(P) and ICC. |
基因名全称 | v-myc myelocytomatosis viral oncogene homolog(avian) |
蛋白名全称 | Myc proto-oncogene protein |
推荐稀释比 | Western blot(WB) 1:500~2000 Immunohistochemistry in paraffin section (IHC) 1:50~400 Immunocytochemistry 1:50~400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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